Alzheimer's Disease

The term CCSVI comes from vascular surgeon Paulo Zamboni of the University of Ferrara in Italy. Dr. Zamboni attributes the cause of multiple sclerosis to CCSVI. He attributes the cause of CCSVI to stenosis of jugular and thoracic veins. What is even more interesting is that he has been having remarkable success treating MS patients with balloon angioplasty to open the veins. Some surgeons prefer to use stents.

The role venous drainage issues play in the brain in causing neurodegenerative diseases is not new, however. I have been writing about it since 1987. If you do a Google search for "stenosis Alzheimer's" or "NPH Alzheimer's" you will find an article I published in 1990 calling for epidemiological research into the role of venous drainage issues in the brain in Alzheimer's disease.

When I first started looking for a possible cause of normal pressure hydrocephalus (NPH) I found an old neurology textbook by Adams and Victor. In the section on NPH it stated that, "A matter of considerable interest is the role of blockage of the dural sinuses (the large main veins of the brain) in tension hydrocephalus. The problem is that blockages are rarely found."

In my opinion they were never found because researchers were focused on blockages in the first place, and in the second place they limited their search to inside the skull. In this regard back pressure against the vertebral veins, not blockage of the dural sinuses may be the cause of NPH. Furthermore, the back pressure may occur outside the skull in the upper cervical spine. Regardless of the source of blockage or back pressure, venous drainage issues in the brain can affect the CSF pressure gradient, which can lead to NPH as I will explain later.

Interestingly, in this regard, AD is oftentimes associated with NPH. NPH has also been associated, albeit less frequently, with Parkinson's Disease (PD). Even now, however, NPH is still, in my opinion, wrongly considered to be a separate and distinct condition and I believe it is one of the root causes of many neurodegenerative diseases.

In addition to resolving signs and symptoms in multiple sclerosis patients, solving venous drainage problems in the brain, such as CCSVI, may similarly lead to a cure for other neurodegenerative diseases, such as AD and PD. It may also be the answer to prevention of these conditions.

The surgical liberation procedure and upper cervical chiropractic brainstem and venous liberation correction may offer hope for a cure and prevention of AD.

History of AD,

According to western medical history books, a German doctor, Alois Alzheimer, discovered the condition in 1907 that would forever be tied to his family name. But he didn't exactly discover the condition. He just gave it a name.

Note: the picture below is supposedly of the first Alzheimer's patient. More accurately speaking, she was the first one to be recognized by western medical sciences.

Pathology of AD

Alzheimer's disease is associated with some unusual pathology. The pathological findings include neurofibrillary tangles and amyloid plaques mentioned above, as well as beta amyloidosis and amyloid precursor proteins, tau proteins and increased lipid levels in the brain.

Amyloid cells were so named because they were once thought to be composed of starches. The word amyloid means a non-nitrogenous starchlike substance. Instead, they turned out to be proteins that are normally shaped into strands of microtubules. Like all tubes, microtubules are perfect for structural strength, as well as the conduction of chemicals.

NOTE: the picture below is an amyloid strand that has become bent and is starting to unravel.

Note: the picture below is an amyloid strand that has become completely unraveled into a distorted beta amyloid sheet.

Note: the picture below shows the process by which the enzyme gamma secretase breaks down amyloid precursor proteins (APP) turning them into sheets of beta amyloid plaques that attach themselves to nerves.

With regards to the symptoms of Alzheimer's our page on dysautonomia may also be of interest.

For those interested, AD and it's relationship to NPH is discussed in depth in my book The Downside of Upright Posture - The Anatomical Causes of Alzheimer's, Parkinson's Multiple Sclerosis.

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